منابع مشابه
Mixed Lymphocyte Culture Responses of Mice
Cellular responses in vitro to H-2D region histocompatibility antigens were demonstrated to be under the genetic control of two or three (P = 0.013) independently segregating loci. The H-2 region itself accounts for one of these loci, however, its activity appears to be dependent upon an association with other non-H-2-associated genetic information. The ability to stimulate a response and to re...
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Lymphocyte function in rheumatoid arthritis has been assessed by the mixed lymphocyte culture assay. In contrast to previous studies, no difference was found between lymphocytes from healthy volunteers and patients with rheumatoid arthritis. An occasional patient's lymphocytes failed to respond on a given day, but were normal on restudy. All 44 arthritic patient's lymphocytes underwent blast tr...
متن کاملMixed lymphocyte culture and graft rejection.
while in the midst of a rejection epiria. The degree of specilk reactivity icnts posttransplant nephrectomy or, 'he reactions of peripheral leukocytes ive depletion of cells directed against · example, patient 2 (HL-A2, 28,17, lining (HL-A2, 28;14, 27) was unJd toward targets bearing (HL-AI, , the phenotypes (I-IL-A 2, W32; 8, ). Similarly patient 4 (HL-A 9, 11; · with (HL-A 2, 11 ;W5, W15) de1...
متن کاملSequential responses of mouse spleen T cells in mixed lymphocyte culture-induced cytolysis
T cells triggered to blast transformation and proliferation by histoincompatible cells have the capacity of reverting "back" to lymphocytes. These "secondary" lymphocytes and their progeny cells are able to respond repeatedly to the same allogeneic stimulus in vitro.
متن کاملSuccessful bone marrow transplantation against mixed lymphocyte culture barrier.
If bone marrow transplantation is to become widely applicable in the treatment of patients with leukemia and aplastic anemia, the necessity to have a perfectly histocompatible donor must be overcome. In an effort to define the roles of HL-A type and mixed lymphocyte culture (MLC) reactivity in the determination of successful engraftment and the occurrence of graftversus-host disease (GVHD), we ...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1974
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.139.4.851